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STAGE 3 WOUND ENVIRONMENT Clinical Outcomes and Quantitative Evidence Alginate absorption capacity: up to 20–30× weight Hydrofiber dressings: → Reduction in wound size by ~30–50% over 4–6 weeks (observational cohorts) NPWT in Stage 3–4 ulcers: → Accelerated granulation formation by ~40% compared to standard care (systematic reviews) Critical Interpretation For Stage 3 pressure injuries with slough, alginate or hydrofiber dressings are first-line, particularly in moderate-to-heavy exudate

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